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results found for 'Bacteria'.
- The gut microbiome—the community of bacteria and viruses in the intestines—plays a key role in the development of the immune system and in protection against viral infections. At the same time, certain viruses can disrupt both the immune system and the gut microbiome. However, the relationship between viral activity and the gut microbiome, and the role these factors play in ME/CFS, remain poorly…
- Resistance against β-lactam antibiotics is a serious health issue. Often it is caused by bacteria producing enzymes capable of inactivating these antibiotics, β-lactamases. This can be prevented by combining the antibiotic with a compound able to inhibit the bacterial enzyme. AimThe aim of this project was to find new β-lactamase inhibitors. To achieve this a large botanical extract library was…
- Bacteria can become resistant against beta-lactam antibiotics (Penicillin) by replacing their 3-4 peptide crosslinks by 3-3 crosslinks in the peptidoglycan layer in their cell wall that gives the bacterium its shape and protects it against mechanical stress. Peptidolglycan consists of a network of sugars strands that are interconnected by peptide crossbridges. Hardly anything was known about the…
- Researchers propose the FunHitDisco, a Fungal Hit Discovery Platform. Read how they will use this to discover antifungal drugs.
- Read how researchers will use genome sequencing to study the fungal genus Candida in hospitals to limit its transmission.
- Symptomen bij patiënten met ME/CVS kunnen ontstaan door verschillende factoren. Eén van deze factoren is dat de darmflora niet meer in balans is.
- Researchers will determine the effectiveness of antibiotic stewardship programs in the intensive care unit and formulate recommendations for implementation.
- Read how the COMBAT-AMR project will develop a standardised toolbox specifically for designing antibiotic combination treatments.
- Read how this project contributes to the implementation and updates of tools in long-term care.
- Infections with antibiotic-resistant bacteria are a major threat to public health. Due to globalisation and poor use of antibiotics, resistance is spreading rapidly. Moreover, few new antibiotics have come onto the market in the last 20 years.AimIn this international project, researchers have been using the latest high-throughput screens to look for new combinations of drugs that can effectively…
- Vancomycin-resistant Enterococcus faecium (VRE) is a multi-resistant bacterium, capable of causing outbreaks in hospitals. This project aims to determine the best VRE screening protocol.
- Read how researchers will create an implementation tool to improve compliance with infection prevention measures by physicians in hospitals.