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- Infections with antibiotic-resistant bacteria are a major threat to public health. Due to globalisation and poor use of antibiotics, resistance is spreading rapidly. Moreover, few new antibiotics have come onto the market in the last 20 years.AimIn this international project, researchers have been using the latest high-throughput screens to look for new combinations of drugs that can effectively…
- Read how researchers will create an implementation tool to improve compliance with infection prevention measures by physicians in hospitals.
- Vancomycin-resistant Enterococcus faecium (VRE) is a multi-resistant bacterium, capable of causing outbreaks in hospitals. This project aims to determine the best VRE screening protocol.
- The project aims to provide broad insight into current risk factors for primary invasive Group A Streptococcus and the effect of the recently-expanded antibiotic prophylaxis guideline to prevent secondary iGAS infections.
- Researchers will work with out-of-hour primary care services to create a national learning community to reduce antibiotic prescriptions.
- The use of plastic products, including packaging material, textiles, and rubber tires, can result in the release of tiny plastic particles in the environment. These tiny plastic particles, known as micro- and nanoplastics (MNPs), are increasingly found in our environment, including drinking water and food. However, we know little about the exact exposure to these MNPs and their potential human…
- Methicillin-resistant Staphylococcus aureus (MRSA) is characterised by clonal spread. MRSA clones are unequally distributed across the world and different clones are dominant at different times. AimThe MACOTRA project studied the interaction between MRSA, humans and the environment. The researchers used mathematical models to gain a better understanding of MRSA dynamics.ResultsA main predictor of…
- Kwetsbare ouderen die thuiszorg ontvangen of in een zorginstelling verblijven krijgen vaak antibiotica voorgeschreven. Bijna 60% daarvan komt voor rekening van urineweginfecties.
- Resistance to antibiotics is increasing worldwide and alternatives are sought for antimicrobial treatment. AimThe overall purpose was to explore and identify antibiotics and non-antibiotics more active in combination than alone (called synergism) against multi- drug resistant bacteria. The tasks of the EMC involved the overall coordination of the project, identification of synergistic combinations…
- Project descriptionMycobacterium tuberculosis is the causative agent of tuberculosis (TB), a disease responsible for almost 1.5 million deaths per year. In recent years, different classes of drug resistant strains have emerged, making the discovery of novel tuberculostatic drugs a major priority. A major disadvantage of most existing and new TB compounds is that they target a single molecule…
- The use of plastic materials, such as packaging, textiles and rubber tyres, can lead to the release of small plastic particles into the environment, micro- and nanoplastic particles (MNPs). MNPs have been found in our environment and in our bodies. We still know little about the potential health risks of MNPs.MOMENTUM 2.0 is a follow-up to the 3-year MOMENTUM project to assess the human health…
- Due to rapidly increasing antimicrobial resistance (AMR) worldwide, our current arsenal of antibiotics is becoming less and less effective in treating bacterial infections. After new antibiotics are introduced, bacteria quickly develop resistance against them. As a result, the return on investment in new antibiotics is minimal and their supply is scarce. A sustainable introduction is only possible…