Cryo-electron microscopy as diagnostic tool to reveal the molecular & cellular architecture in healthy & pathogenic cells

Titel: C-type lectins and their role in the immune system.
Auteur: K Bloem

Titel: The post-docking role of Synaptotagmin1 and Munc18-1 in mouse chromaffin cells.
Auteur: G.H. Kedar

Titel: Synaptic effects of Munc18-1 alternative splicing and protein modifications
Auteur: M. Meijer

Titel: Water and ion homeostasis in the developing brain: disease models impacting understanding of physiology.
Auteur: M. Dubey

Titel: Kinetic models for synaptic vesicle release
Auteur: S. Schotten

Titel: C2 domain function in healthy and diseased brain
Auteur: A. Giniatullina

Titel: The role of presynaptic proteins in maintaining neuronal viability
Auteur: T. Santos

Titel: Trafficking and secretion of neuropeptides in mouse hippocampal neurons
Auteur: M. Farina

Titel: Dissecting the role of Fbxo41 in neuronal development and signaling.
Auteur: C.R. King

Titel: Mechanisms understanding synapse formation and post-synaptic receptor targeting.
Auteur: F Farzana

Titel: Organizing sites for regulated secretion in adrenal chromaffin cells.
Auteur: J. Kurps

Titel: Comparing and contrasting white matter disorders: a neuropathological approach to pathophysiology
Auteur: M. Bugiani

Titel: Mice with megalencephalic leukoencephalopathy with cysts: A developmental angle
Auteur: Dubey, Mohit, Bugiani, Marianna, Ridder, Margreet C., Postma, Nienke L., Brouwers, Eelke, Polder, Emiel, Jacobs, J. Gerbren, Baayen, Johannes C., Klooster, Jan, Kamermans, Maarten, Aardse, Romy, de Kock, Christiaan P. J., Dekker, Marien P., van Weering, Jan R. T., Heine, Vivi M., Abbink, Truus E. M., Scheper, Gert C., Boor, Ilja, Lodder, Johannes C., Mansvelder, Huibert D., van der Knaap, Marjo S.
Magazine: Annals of Neurology

Titel: VPS35 depletion does not impair presynaptic structure and function
Auteur: Vazquez-Sanchez, Sonia, Bobeldijk, Sander, Dekker, Marien P., van Keimpema, Linda, van Weering, Jan R. T.
Magazine: Scientific Reports

Titel: CNS myelin induces regulatory functions of DC-SIGN expressing antigen-presenting cells via cognate interaction with MOG.
Auteur: J.J. García-Vallejo, J.M. Ilarregui, H. Kalay, S. Chamorro, N. Koning, W.W. Unger, M. Ambrosini, V. Montserrat, R. J. Fernandes, S. C. M. Bruijns, J.R.T. van Weering, N.J. Paauw, T. O’Toole, J. van Horssen, P. van der Valk, K. Nazmi, J.G.M. Bolscher, J. Bajramovic, C.D. Dijkstra, B.A. ’t Hart, and Y. van Kooyk
Magazine: Journal of Experimental Medicine

Titel: The UPR reduces glucose metabolism via IRE1 signaling
Auteur: van der Harg, Judith M., van Heest, Jessica C., Bangel, Fabian N., Patiwael, Sanne, van Weering, Jan R.T., Scheper, Wiep
Magazine: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Titel: Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes
Auteur: Brouwer, Ineke, Giniatullina, Asiya, Laurens, Niels, van Weering, Jan R. T., Bald, Dirk, Wuite, Gijs J. L., Groffen, Alexander J.
Magazine: Nature Communications

Titel: Extension of Helix 12 in Munc18-1 Induces Vesicle Priming
Auteur: Munch, A. S., Kedar, G. H., van Weering, J. R. T., Vazquez-Sanchez, S., He, E., Andre, T., Braun, T., Sollner, T. H., Verhage, M., Sorensen, J. B.
Magazine: Journal of Neuroscience

Titel: MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission
Auteur: He, Enqi, Lozano, Miguel A Gonzalez, Stringer, Sven, Watanabe, Kyoko, Sakamoto, Kensuke, den Oudsten, Frank, Koopmans, Frank, Giamberardino, Stephanie N, Hammerschlag, Anke, Cornelisse, L Niels, Li, Ka Wan, van Weering, Jan, Posthuma, Danielle, Smit, August B, Sullivan, Patrick F, Verhage, Matthijs
Magazine: Human Molecular Genetics

Titel: Development of dendritic tonic GABAergic inhibition regulates excitability and plasticity in CA1 pyramidal neurons
Auteur: M. Groen, O. Paulsen, E. Perez-Garci, T. Nevian, J. Wortel, R. Dekker, H. Mansvelder, A. van Ooyen, and R. Meredith; Journal of Neurophysiology
Magazine: Journal of Neurophysiology

Titel: Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons
Auteur: Emperador Melero, Javier, Nadadhur, Aishwarya G., Schut, Desiree, Weering, Jan V., Heine, Vivi M., Toonen, Ruud F., Verhage, Matthijs
Magazine: Stem Cell Reports

Titel: A Post-Docking Role of Synaptotagmin 1-C2B Domain Bottom Residues R398/399 in Mouse Chromaffin Cells
Auteur: Kedar, G. H., Munch, A. S., van Weering, J. R. T., Malsam, J., Scheutzow, A., de Wit, H., Houy, S., Tawfik, B., Sollner, T. H., Sorensen, J. B., Verhage, M.
Magazine: Journal of Neuroscience

Titel: Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly
Auteur: Meijer, Marieke, Dörr, Bernhard, Lammertse, Hanna CA, Blithikioti, Chrysanthi, van Weering, Jan RT, Toonen, Ruud FG, Söllner, Thomas H, Verhage, Matthijs
Magazine: EMBO Journal

Titel: Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B
Auteur: Dominguez, Natalia, van Weering, Jan R. T., Borges, Ricardo, Toonen, Ruud F. G., Verhage, Matthijs
Magazine: Journal of Neurochemistry

Titel: Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset
Auteur: D. Chiasserini, J.R.T. van Weering, S.R. Piersma, T.V. Pham, A . Malekzadeh, C.E. Teunissen, H. de Wit, C.R. Jiménez
Magazine: Journal of Proteomics

Titel: Vitrification of Tokuyasu-style immuno-labeled sections for correlative cryo light microscopy and cryo electron tomography
Auteur: E. Bos, L. Hussaarts, J.R.T. van Weering, M.H. Ellisman, H. de Wit, A.J. Koster
Magazine: Journal of Structural Biology

Titel: Strain Differences in Presynaptic Function
Auteur: Lenselink, A. Mariette, Rotaru, Diana C., Li, Ka Wan, van Nierop, Pim, Rao-Ruiz, Priyanka, Loos, Maarten, van der Schors, Roel, Gouwenberg, Yvonne, Wortel, Joke, Mansvelder, Huibert D., Smit, August B., Spijker, Sabine
Magazine: Journal of Biological Chemistry

Titel: CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons
Auteur: Farina, Margherita, van de Bospoort, Rhea, He, Enqi, Persoon, Claudia M, van Weering, Jan RT, Broeke, Jurjen H, Verhage, Matthijs, Toonen, Ruud F
Magazine: eLife

Titel: Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains
Auteur: Geerts, Cornelia J., Mancini, Roberta, Chen, Ning, Koopmans, Frank T. W., Li, Ka Wan, Smit, August B., van Weering, Jan R. T., Verhage, Matthijs, Groffen, Alexander J. A.
Magazine: PLoS ONE

Titel: Megalencephalic leukoencephalopathy with cysts: the Glialcam -null mouse model
Auteur: Bugiani, Marianna, Dubey, Mohit, Breur, Marjolein, Postma, Nienke L., Dekker, Marien P., ter Braak, Timo, Boschert, Ursula, Abbink, Truus E. M., Mansvelder, Huibert D., Min, Rogier, van Weering, Jan R. T., van der Knaap, Marjo S.
Magazine: Annals of Clinical and Translational Neurology

Titel: The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity
Auteur: Saeloh, Dennapa, Tipmanee, Varomyalin, Jim, Kin Ki, Dekker, Marien P., Bitter, Wilbert, Voravuthikunchai, Supayang P., Wenzel, Michaela, Hamoen, Leendert W.
Magazine: PLoS Pathogens

Titel: Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients
Auteur: van Eijndhoven, Monique A.J., Zijlstra, Josée M., Groenewegen, Nils J., Drees, Esther E.E., van Niele, Stuart, Baglio, S. Rubina, Koppers-Lalic, Danijela, van der Voorn, Hans, Libregts, Sten F.W.M., Wauben, Marca H.M., de Menezes, Renee X., van Weering, Jan R.T., Nieuwland, Rienk, Visser, Lydia, van den Berg, Anke, de Jong, Daphne, Pegtel, D. Michiel
Magazine: Journal of Clinical Investigation