Targeted Nanotherapeutics: aiming at the resolution of liver fibrosis

Titel: TG101348, a selective JAK2 antagonist, ameliorates hepatic fibrogenesis in vivo
Auteur: Akcora, Büsra Öztürk, Dathathri, Eshwari, Ortiz-Perez, Ana, Gabriël, Alexandros Vassilios, Storm, Gert, Prakash, Jai, Bansal, Ruchi
Magazine: FASEB Journal

Titel: TARGETING NOTCH SIGNALING PATHWAY BY SMALL MOLECULE GAMMA SECRETASE INHIBITOR BMS-708163 ATTENUATES EARLY LIVER FIBROGENESIS IN VIVO

Titel: Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer
Auteur: Binnemars-Postma, Karin; Bansal, Ruchi; Storm, Gert; Prakash, Jai
Magazine: The FASEB Journal

Titel: Targeting liver inflammation using Mincle-targeted liposomes as a novel drug delivery system
Auteur: Szachniewicz, M. ; Bartneck, M. ; Tacke, F. ; Bansal, R.
Magazine: Hepatology

Titel: Inhibition of canonical WNT signaling pathway by ß-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12
Auteur: Akcora, Büsra Öztürk, Storm, Gert, Bansal, Ruchi
Magazine: BBA Molecular basis of disease

Titel: Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model
Auteur: Öztürk Akcora, Büsra; Storm, Gert; Prakash, Jai; Bansal, Ruchi
Magazine: Scientific Reports

Titel: Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases
Auteur: Bansal, Ruchi, Nakagawa, Shigeki, Yazdani, Saleh, van Baarlen, Joop, Venkatesh, Anu, Koh, Anna P, Song, Won-Min, Goossens, Nicolas, Watanabe, Hideo, Beasley, Mary B, Powell, Charles A, Storm, Gert, Kaminski, Naftali, van Goor, Harry, Friedman, Scott L, Hoshida, Yujin, Prakash, Jai
Magazine: Experimental and Molecular Medicine

Titel: Therapeutic inhibition of spleen tyrosine kinase in inflammatory macrophages using PLGA nanoparticles for the treatment of non-alcoholic steatohepatitis
Auteur: Kurniawan, Dhadhang Wahyu, Jajoriya, Arun Kumar, Dhawan, Garima, Mishra, Divya, Argemi, Josepmaria, Bataller, Ramon, Storm, Gert, Mishra, Durga Prasad, Prakash, Jai, Bansal, Ruchi
Magazine: Journal of Controlled Release

Titel: Drug targeting to myofibroblasts: Implications for fibrosis and cancer
Auteur: Yazdani, Saleh; Bansal, Ruchi; Prakash, Jai
Magazine: Advanced Drug Delivery Reviews

Titel: Significance of Integrin Alpha 11 in phenotypic regulation of Hepatic stellate cells in Liver fibrosis

Titel: Clinical advancements in the targeted therapies against liver fibrosis
Auteur: Ruchi Bansal, Beata Nagórniewicz, and Jai Prakash
Magazine: Mediators of Inflammation
Link: https://www.hindawi.com/journals/mi/aip/7629724/

Titel: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice
Auteur: Poosti Fariba, Bansal Ruchi, Yazdani Saleh, Prakash Jai, Beljaars Leonie, Born Jacob van den, de Borst Martin H., van Goor Harry, Hillebrands Jan-Luuk, Poelstra Klaas
Magazine: Oncotarget
Link: http://www.impactjournals.com/oncotarget/

Titel: RELAXIN-COATED IRON-OXIDE MAGNETIC NANOPARTICLES AS A NOVEL THERANOSTIC APPROACH FOR DIAGNOSIS AND TREATMENT OF LIVER FIBROSIS
Auteur: R. Bansal, B. Nagorniewicz, J. Prakash, G. Storm
Magazine: European Journal of Gastroenterology and Hepatology
Link: http://ueg.sagepub.com/content/4/5_suppl

Titel: Integrin Alpha 11 Significance in Phenotypic Transformation of Hepatic Stellate Cells in Liver Fibrosis
Auteur: Bansal, R., Nakagawa, S., Friedman, S.L., Hoshida, Y., Prakash, J.
Magazine: Journal of Hepatology

Titel: The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis
Auteur: Ruchi Bansal; Joop van Baarlen; Gert Storm; Jai Prakash
Magazine: Scientific Reports

Titel: Inhibition of canonical WNT signaling pathway by ß-catenin/CBP inhibitor ICG001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12
Auteur: Akcora BÖ, Storm G, Prakash J, Bansal R
Magazine: Journal of Hepatology

Titel: TARGETING LIVER INFLAMMATION USING MINCLE-TARGETED LIPOSOMES AS A NOVEL DRUG DELIVERY SYSTEM
Auteur: M Szachniewicz; M Bartneck; F Tacke; R Bansal
Magazine: Alcohol and Alcoholism

Titel: Engineered Relaxin as theranostic nanomedicine to diagnose and ameliorate liver cirrhosis
Auteur: Nagórniewicz, Beata, Mardhian, Deby F., Booijink, Richell, Storm, Gert, Prakash, Jai, Bansal, Ruchi
Magazine: Nanomedicine

Titel: Relaxin-coated superparamagnetic iron-oxide nanoparticles as a novel theranostic approach for the diagnosis and treatment of liver fibrosis
Auteur: Bansal R, Beata Nagorniewicz, Bettie Klomphaar, Gert Storm, Jai Prakash
Magazine: Journal of Hepatology

Titel: Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system
Auteur: PIM J. VAN DEN BERG, RUCHI BANSAL, KHALID DAOUDI, WIENDELT STEENBERGEN, JAI PRAKASH
Magazine: Biomedical Optics Express
Link: https://www.osapublishing.org/boe/abstract.cfm?uri=boe-7-12-5081

Titel: Selective delivery of interferon gamma to renal interstitial myofibroblasts: A novel strategy for the treatment of renal fibrosis
Auteur: Poosti F, Bansal R, Yazdani S, Prakash J, Post E, Klok P, Van den Born J, de Borst MH, Van Goor H, Poelstra K, Hillebrands JH
Magazine: FASEB Journal

Titel: National Scholar Award and Travel Award: Targeting liver inflammation using Mincle-targeted liposomes as a novel drug delivery system
Link: https://www.ueg.eu/awards-grants/ueg-week-awards/national-scholar-award/

Titel: Hoe Gaat Het Eigenlijk met Ruchi Bansal
Link: http://www.hepatologie.org/files/LEVER%203_15.pdf

Titel: Integrin alpha 11 identified as a novel therapeutic target that regulates fibrosis