Impact of reducing colistin use on colistin resistance in humans and poultry in Indonesia

Antimicrobial resistance threatens the effectiveness of life-saving antibiotics. In Indonesia, the antibiotic colistin was banned from livestock use in 2020 because it is a last-resort medicine for humans.

Aim

The COINCIDE project studied whether the ban of the antibiotic colistin in Indonesia reduced resistance in people and poultry.

Results

Research in Central Java showed that colistin resistance is rare and that farmers largely comply with the ban. The project also developed an affordable laboratory test and strengthened local laboratory capacity. At the same time, the study found that antibiotics are still often used without prescription in the community. COINCIDE shows that coordinated One Health policies can work, but continued surveillance, communication, and responsible antibiotic use remain essential.

Products

Title: Miss, I want itchy medicine": Understanding what, why, and how antibiotics are used in Central Java province, Indonesia through the drug bag method
Author: Naing SY, Schneiders ML, Ningrum D, Nurdianti T, Severin J, Peeters Grietens K, Wagenaar JA, Karuniawati A. "Miss, I want itchy medicine": Understanding what, why, and how antibiotics are used in Central Java province, Indonesia through the drug bag method.
Magazine: PLOS Glob Public Health
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12962538/
Title: Impact of reducing colistin use on colistin resistance in Escherichia coli isolated from humans and poultry in Indonesia (COINCIDE): A protocol for a multisectoral, transdisciplinary One Health study
Author: Naing SY, Severin J, Zomer A, Kuntaman K, Suandy I, Sunandar S, Rachmawati A, Nurbiyanti N, Schneiders ML, Grietens KP, Widya A, van der Graaf-van Bloois L, Pruvot M, Nobrega D, Karuniawati A, Wagenaar JA.
Magazine: One Health
Start- and endpage: 22-
Link: https://www.sciencedirect.com/science/article/pii/S2352771426000315?via%3Dihub
Title: THE LAST LINE: SAFEGUARDING THE ANTIBIOTICS - BATAS TERAKHIR: MENGAMANKAN ANTIBIOTIK
Author: Tri Nurdianti and Soe Yu Naing
Link: https://www.researchgate.net/publication/399719454_THE_LAST_LINE_SAFEGUARDING_THE_ANTIBIOTICS_photo_exhibition_COINCIDE_study_Indonesia

Features

Project number:
10570132110006
Duration: 100%
2022
2025
Part of programme:
Related funding round:
Project lead and secretary:
dr. A.L. Zomer
Responsible organisation:
Universiteit Utrecht