From Autoreactive B cells to Immunological Remission in Rheumatoid Arthritis
Reumatoïde artritis is een chronische auto-immuunziekte die opvlamt als de behandeling stopt. Onderzoekers hebben ontdekt dat, ondanks behandeling, specifieke afweercellen in patiënten aanhoudend actief blijven. Onderzoekers zullen single cel technologie gebruiken om deze immunologische ziekteactiviteit te begrijpen, de cellen tot rust te brengen en zo chroniciteit van ziekte te doorbreken.
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Titel: Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis.
Auteur: Kroos S, Kampstra ASB, Toes REM, Slot LM, Scherer HU
Magazine: Arthritis Res Ther.
Link: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-022-02919-2
Auteur: Kroos S, Kampstra ASB, Toes REM, Slot LM, Scherer HU
Magazine: Arthritis Res Ther.
Link: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-022-02919-2
Titel: Multifunctional, Multivalent PIC Polymer Scaffolds for Targeting Antigen-Specific, Autoreactive B Cells
Auteur: Hendy Kristyanto, Miles D Holborough-Kerkvliet, Lianne Lelieveldt, Yvonne Bartels, Roel Hammink, Karin A J van Schie, Rene E M Toes, Kimberly M Bonger, Hans Ulrich Scherer
Magazine: ACS Biomater Sci Eng
Begin- en eindpagina: 1486-1493
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35259296/
Auteur: Hendy Kristyanto, Miles D Holborough-Kerkvliet, Lianne Lelieveldt, Yvonne Bartels, Roel Hammink, Karin A J van Schie, Rene E M Toes, Kimberly M Bonger, Hans Ulrich Scherer
Magazine: ACS Biomater Sci Eng
Begin- en eindpagina: 1486-1493
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35259296/
Titel: Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts
Auteur: Reijm S, Kwekkeboom JC, Blomberg NJ, Suurmond J, van der Woude D, Toes RE, Scherer HU
Magazine: JCI Insight
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/37725442/
Auteur: Reijm S, Kwekkeboom JC, Blomberg NJ, Suurmond J, van der Woude D, Toes RE, Scherer HU
Magazine: JCI Insight
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/37725442/
Titel: Beyond the surface - Autoreactive B cells in human autoimmune diseases.
Auteur: Scherer HU
Magazine: Semin Arthritis Rheum
Link: https://www.sciencedirect.com/science/article/pii/S0049017223001579
Auteur: Scherer HU
Magazine: Semin Arthritis Rheum
Link: https://www.sciencedirect.com/science/article/pii/S0049017223001579
Titel: From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis
Auteur: Hans Ulrich Scherer, Diane van der Woude, Rene E M Toes
Magazine: Nat Rev Rheumatol
Link: https://www.nature.com/articles/s41584-022-00786-4
Auteur: Hans Ulrich Scherer, Diane van der Woude, Rene E M Toes
Magazine: Nat Rev Rheumatol
Link: https://www.nature.com/articles/s41584-022-00786-4
Titel: Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts.
Auteur: Sanne Reijm, Joanneke C Kwekkeboom, Nienke J Blomberg, Jolien Suurmond, Diane van der Woude, René EM Toes, Hans U Scherer
Magazine: JCI Insight
Link: https://insight.jci.org/articles/view/172006
Auteur: Sanne Reijm, Joanneke C Kwekkeboom, Nienke J Blomberg, Jolien Suurmond, Diane van der Woude, René EM Toes, Hans U Scherer
Magazine: JCI Insight
Link: https://insight.jci.org/articles/view/172006
Titel: Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data
Auteur: Andreani T, Slot LM, Gabillard S, Strübing C, Reimertz C, Yaligara V, Bakker AM, Olfati-Saber R, Toes REM, Scherer HU, Augé F, Šimaite D
Magazine: NAR Genom Bioinform
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35855325/
Auteur: Andreani T, Slot LM, Gabillard S, Strübing C, Reimertz C, Yaligara V, Bakker AM, Olfati-Saber R, Toes REM, Scherer HU, Augé F, Šimaite D
Magazine: NAR Genom Bioinform
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35855325/
Titel: Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis.
Auteur: Kroos S, Kampstra ASB, Toes REM, Slot LM, Scherer HU
Magazine: Arthritis Res Ther
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/36229887/
Auteur: Kroos S, Kampstra ASB, Toes REM, Slot LM, Scherer HU
Magazine: Arthritis Res Ther
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/36229887/
Titel: Beyond the surface - Autoreactive B cells in human autoimmune diseases.
Auteur: Scherer HU
Magazine: Semin Arthritis Rheum
Link: https://www.sciencedirect.com/science/article/pii/S0049017223001579
Auteur: Scherer HU
Magazine: Semin Arthritis Rheum
Link: https://www.sciencedirect.com/science/article/pii/S0049017223001579
Titel: CAR T cells for systemic autoimmune diseases
Auteur: Invited presentation; Dutch CAR-T cell Symposium Inviting organization: Scientific Organizing Committee
Auteur: Invited presentation; Dutch CAR-T cell Symposium Inviting organization: Scientific Organizing Committee
Titel: ASCARA - silencing autoreactive B cells in RA
Auteur: Scherer HU
Auteur: Scherer HU
Titel: Inaugural lecture entitled 'Over barrières en bruggen: auto-immuunziektes op weg naar genezing'.
Auteur: Scherer HU
Link: https://scholarlypublications.universiteitleiden.nl/handle/1887/3762659
Auteur: Scherer HU
Link: https://scholarlypublications.universiteitleiden.nl/handle/1887/3762659