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Dierexperimenteel onderzoek naar urogynaecologische implantaten: relevante uitkomstmaten voor het beschrijven van de afweerreactie.

Projectomschrijving

This systematic review and meta-analysis provide evidence that oestrogen therapy has a beneficial effect on vaginal wound healing, improving tissue quality and tissue strength after surgery. Consequently, it could be hypothesised that long-term surgical outcomes may improve in postmenopausal women when treated with oestrogen, but this needs further investigation.
The outcomes of this study justify further research evaluating the effect of oestrogen-induced improved vaginal wound healing on surgical outcomes, such as recurrence rates of POP, vaginal health, quality of life and sexual function. 

Producten

Titel: Animal experimental research assessing urogynecologicsurgical mesh implants: Outcome measures describing thehost response, a systematic review and meta-analysis
Auteur: Kim W. J. Verhorstert, Aksel N. Gudde, Brita S. Kortz, Jacqueline Limpens, Jan-Paul W. R. Roovers, Carlijn R. Hooijmans, Zeliha Guler
Magazine: Neurourology & Urodynamics

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Samenvatting van de aanvraag

This systematic review and meta-analysis provide evidence that oestrogen therapy has a beneficial effect on vaginal wound healing, improving tissue quality and tissue strength after surgery. Consequently, it could be hypothesised that long-term surgical outcomes may improve in postmenopausal women when treated with oestrogen, but this needs further investigation.
The outcomes of this study justify further research evaluating the effect of oestrogen-induced improved vaginal wound healing on surgical outcomes, such as recurrence rates of POP, vaginal health, quality of life and sexual function. 

Onderwerpen

Kenmerken

Projectnummer:
114024138
Looptijd: 100%
Looptijd: 100 %
2019
2021
Onderdeel van programma:
Gerelateerde subsidieronde:
Projectleider en penvoerder:
Prof. dr. J.P.W.R. Roovers
Verantwoordelijke organisatie:
Amsterdam UMC - locatie AMC