Dierexperimenteel onderzoek naar urogynaecologische implantaten: relevante uitkomstmaten voor het beschrijven van de afweerreactie.

This systematic review and meta-analysis provide evidence that oestrogen therapy has a beneficial effect on vaginal wound healing, improving tissue quality and tissue strength after surgery. Consequently, it could be hypothesised that long-term surgical outcomes may improve in postmenopausal women when treated with oestrogen, but this needs further investigation.
The outcomes of this study justify further research evaluating the effect of oestrogen-induced improved vaginal wound healing on surgical outcomes, such as recurrence rates of POP, vaginal health, quality of life and sexual function.