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The effect of HPV16 peptide vaccination on the local and systemic immune response in woman with HPV16 + pre-malignant disorders of the uterine cervix

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Titel: Tumor-infiltrating CD14-positive myeloid cells and CD8-positive T-cells prolong survival in patients with cervical carcinoma
Auteur: de Vos van Steenwijk PJ, Ramwadhdoebe TH, Goedemans R, Doorduijn EM, van Ham JJ, Gorter A, van Hall T, Kuijjer ML, van Poelgeest MI, van der Burg SH, Jordanova ES.
Magazine: International Journal of Cancer
Titel: Surgery followed by Persistence of High-Grade Squamous Intraepithelial Lesions Is Associated with the Induction of a Dysfunctional HPV16-Specific T-Cell Response
Auteur: de Vos van Steenwijk PJ, Piersma SJ, Welters MJ, van der Hulst JM, Fleuren G, Hellebrekers BW, Kenter GG, van der Burg SH
Magazine: Clinical Cancer Research
Titel: Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses
Auteur: Welters MJ, Kenter GG, de Vos van Steenwijk PJ, Löwik MJ, Berends-van der Meer DM, Essahsah F, Stynenbosch LF, Vloon AP, Ramwadhdoebe TH, Piersma SJ, van der Hulst JM, Valentijn AR, Fathers LM, Drijfhout JW, Franken KL, Oostendorp J, Fleuren GJ, Melief CJ, van der Burg SH
Magazine: Proceedings of the National Academy of Sciences USA
Titel: A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions
Auteur: Peggy J. de Vos van Steenwijk Tamara H. Ramwadhdoebe Margriet J. G. Lo¨wik Caroline E. van der Minne Dorien M. A. Berends-van der Meer Lorraine M. Fathers A. Rob P. M. Valentijn Jaap Oostendorp Gert Jan Fleuren Bart W. J. Hellebrekers Marij J. P. Welters Mariette I. van Poelgeest Cornelis J. M. Melief Gemma G. Kenter Sjoerd H. van der Burg
Magazine: Cancer immunology and immunotherapy
Titel: Surgery followed by persistence of high-grade squamous intraepithelial lesions is associated with the induction of a dysfunctional HPV16-specific T-cell response
Auteur: de Vos van Steenwijk PJ1, Piersma SJ, Welters MJ, van der Hulst JM, Fleuren G, Hellebrekers BW, Kenter GG, van der Burg SH.
Magazine: Clinical Cancer Research
Titel: Surgery followed by persistence of high-grade squamous intraepithelial lesions is associated with the induction of a dysfunctional HPV16-specific T-cell response.
Auteur: de Vos van Steenwijk PJ, Piersma SJ, Welters MJ, van der Hulst JM, Fleuren G, Hellebrekers BW, Kenter GG, van der Burg SH.
Titel: An unexpectedly large polyclonal repertoire of HPV-specific T cells is poised for action in patients with cervical cancer
Auteur: de Vos van Steenwijk PJ1, Heusinkveld M, Ramwadhdoebe TH, Löwik MJ, van der Hulst JM, Goedemans R, Piersma SJ, Kenter GG, van der Burg SH.
Magazine: Cancer Research
Titel: An unexpectedly large polyclonal repertoire of HPV-specific T cells is poised for action in patients with cervical cancer
Auteur: de Vos van Steenwijk PJ, Heusinkveld M, Ramwadhdoebe TH, Löwik MJ, van der Hulst JM, Goedemans R, Piersma SJ, Kenter GG, van der Burg SH
Magazine: Cancer Research
Titel: M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells.
Auteur: Heusinkveld M, Goedemans R, Briet RJ, Gelderblom H, Nortier JW, Gorter A, Smit VT, Langeveld AP, Jansen JC, van der Burg SH. Int J Cancer. 2011 Oct 24. doi: 10.1002/ijc.26497. [Epub ahead of print]
Magazine: International Journal of Cancer
Titel: Immunology and Immunotherapy of high grade cervical lesions and cancer
Auteur: Promotores: Prof. S.H. van de Burg en Prof. dr G.G.Kenter Co-promotores: Dr. M.I.E v. Poelgeest en Dr. M.Welters

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Kenmerken

  • Projectnummer:
    92003425
  • Looptijd: 100%
    Looptijd: 100 %
    2007
    2016
  • Gerelateerde programma's:
  • Gerelateerde subsidieronde:
  • Projectleider en penvoerder:
    Prof. dr. G.G. Kenter
  • Verantwoordelijke organisatie:
    Centrum voor Gynaecologische Oncologie Amsterdam