Securing brain Health by personalised treatment of INdividuals with cOvert Brain Infarcts (SHINOBI)
1 op de 4 ouderen heeft een verhoogd risico op beroerte en dementie doordat zij zonder het te weten een herseninfarct hebben doorgemaakt. In dit onderzoek neem ik deze ‘stille’ infarcten onder de loep om kenmerken en mechanismen te ontrafelen die een gepersonaliseerde behandeling tegen beroerte en dementie mogelijk maken.
Producten
Titel: Incidence and Prognostic Indicators of Dementia in Patients With Covert Brain Infarction, Transient Ischemic Attack, and Stroke: The Population-Based Rotterdam Study
Auteur: Jacqueline J Claus, Camiel V J Box, Elisabeth J Vinke, Mathijs T Rosbergen, Bernhard P Berghout, Meike W Vernooij, M Arfan Ikram, M Kamran Ikram, Frank J Wolters
Magazine: J Am Heart Assoc
Link: https://doi.org/10.1161/JAHA.124.041316
Auteur: Jacqueline J Claus, Camiel V J Box, Elisabeth J Vinke, Mathijs T Rosbergen, Bernhard P Berghout, Meike W Vernooij, M Arfan Ikram, M Kamran Ikram, Frank J Wolters
Magazine: J Am Heart Assoc
Link: https://doi.org/10.1161/JAHA.124.041316
Titel: Asymptomatic carotid artery stenosis, cognitive decline and dementia: a prospective population-based cohort study
Auteur: Camiel V.J. Box, Amos C. Pomp, Qingling Yu, Maryam Kavousi, M. Kamran Ikram, Aad van der Lugt, Daniel Bos, Frank J. Wolters
Magazine: MedRXiv (preprint ahead of publication)
Link: https://doi.org/10.64898/2026.08.18.26360680
Auteur: Camiel V.J. Box, Amos C. Pomp, Qingling Yu, Maryam Kavousi, M. Kamran Ikram, Aad van der Lugt, Daniel Bos, Frank J. Wolters
Magazine: MedRXiv (preprint ahead of publication)
Link: https://doi.org/10.64898/2026.08.18.26360680
Titel: Risk of Cardiovascular Disease With Co-Occurring Covert Brain Infarction and Unrecognized Myocardial Infarction
Auteur: Camiel V J Box, Julie A E van Oortmerssen, Martijn J Tilly, Meike W Vernooij, M Kamran Ikram, Maryam Kavousi, Frank J Wolters
Magazine: J Am Heart Assoc
Link: https://doi.org/10.1161/JAHA.125.042282
Auteur: Camiel V J Box, Julie A E van Oortmerssen, Martijn J Tilly, Meike W Vernooij, M Kamran Ikram, Maryam Kavousi, Frank J Wolters
Magazine: J Am Heart Assoc
Link: https://doi.org/10.1161/JAHA.125.042282
Titel: Long-term Risks and Predictors of Stroke and Dementia in Individuals with Covert Brain Infarction: a Coordinated Meta-Analysis of Eight Community-based Cohorts
Auteur: Camiel V.J. Box, Aïcha Soumaré, Stephanie Debette, Christophe Tzourio, Xiaoqian Zhu, Michael Griswold, Kevin Sullivan, B. Gwen Windham, Matthew R. Scott, Alexa S. Beiser, Sudha Seshadri, Hugo J. Aparicio, Charles DeCarli, Joshua C. Bis, Bruce M. Psaty, Traci M. Bartz, WT Longstreth Jr, Oscar Lopez, Lina Rydén, Silke Kern, Ingmar Skoog, Eric Westman, Huaizhi Ge, [...] & Frank J. Wolters
Magazine: Lancet SSR preprint
Link: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=7305612
Auteur: Camiel V.J. Box, Aïcha Soumaré, Stephanie Debette, Christophe Tzourio, Xiaoqian Zhu, Michael Griswold, Kevin Sullivan, B. Gwen Windham, Matthew R. Scott, Alexa S. Beiser, Sudha Seshadri, Hugo J. Aparicio, Charles DeCarli, Joshua C. Bis, Bruce M. Psaty, Traci M. Bartz, WT Longstreth Jr, Oscar Lopez, Lina Rydén, Silke Kern, Ingmar Skoog, Eric Westman, Huaizhi Ge, [...] & Frank J. Wolters
Magazine: Lancet SSR preprint
Link: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=7305612