Transcription stress Counteracted by Nutritional interventions of Exceptional importance for rare DNA Repair disorders (TC-NER)

Titel: High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice
Auteur: W.P. Vermeij

Titel: A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia
Auteur: He Y, van Mever M, Yang W, Huang L, Ramautar R, Rijksen Y, Vermeij WP, Hoeijmakers JHJ, Harms AC, Lindenburg PW, Hankemeier T.
Magazine: Metabolites

Titel: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside
Auteur: Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP
Magazine: Front Aging

Titel: Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity
Auteur: Oudmaijer CAJ, van den Boogaard WMC, Komninos DSJ, Verwaaijen EJ, van Santen HM, Lilien MR, Hoeijmakers JHJ, Wijnen MHW, van den Heuvel-Eibrink MM, Vermeij WP.
Magazine: Front Pediatr

Titel: Different responses to DNA damage determine ageing differences between organs
Auteur: Vougioukalaki M, Demmers J, Vermeij WP, Baar M, Bruens S, Magaraki A, Kuijk E, Jager M, Merzouk S, Brandt RMC, Kouwenberg J, van Boxtel R, Cuppen E, Pothof J, Hoeijmakers JHJ.
Magazine: Aging Cell

Titel: Gene expression changes in cerebellum induced by dietary restriction
Auteur: Van't Sant LJ, Birkisdóttir MB, Ozinga RA, Gyenis Á, Hoeijmakers JHJ, Vermeij WP, Jaarsma D.
Magazine: Front Mol Neurosci.

Titel: Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice
Auteur: Barnhoorn S, Meima ME, Peeters RP, Darras VM, Leeuwenburgh S, Hoeijmakers JHJ, Vermeij WP, Visser WE.
Magazine: Eur Thyroid J.

Titel: Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health
Auteur: Birkisdóttir MB, Van't Sant LJ, Brandt RMC, Barnhoorn S, Hoeijmakers JHJ, Vermeij WP, Jaarsma D.
Magazine: Front Aging Neurosci

Titel: Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial
Auteur: Oudmaijer CAJ, Minnee RC, Pol RA, van den Boogaard WMC, Komninos DSJ, van de Wetering J, van Heugten MH, Hoorn EJ, Sanders JSF, Hoeijmakers JHJ, Vermeij WP, IJzermans JNM.
Magazine: Trials

Titel: In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
Auteur: Van't Sant LJ, White JJ, Hoeijmakers JHJ, Vermeij WP, Jaarsma D.
Magazine: Acta Neuropathol Commun