Understanding the molecular and cellular basis of Angelman Syndrome

Titel: A disulphide bond in the E2 enzyme Pex4p modulates ubiquitin-conjugating activity

Titel: Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model

Titel: Impaired Neurite Contact Guidance in Ubiquitin Ligase E3a (Ube3a)-Deficient Hippocampal Neurons on Nanostructured Substrates
Auteur: Tonazzini, I., Meucci, S., Van Woerden, G. M., Elgersma, Y., Cecchini, M.
Magazine: Advanced Healthcare Materials

Titel: Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

Titel: Treatment of Cognitive Deficits in Genetic Disorders: A Systematic Review of Clinical Trials of Diet and Drug Treatments

Titel: Interaction of SH-SY5Y Cells with Nanogratings During Neuronal Differentiation: Comparison with Primary Neurons
Auteur: Tonazzini, Ilaria, Cecchini, Alessandra, Elgersma, Ype, Cecchini, Marco
Magazine: Advanced Healthcare Materials

Titel: Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL
Auteur: Nelson, Jessica K, Sorrentino, Vincenzo, Avagliano Trezza, Rossella, Heride, Claire, Urbe, Sylvie, Distel, Ben, Zelcer, Noam
Magazine: Circulation Research

Titel: Treatment of Neurodevelopmental Disorders in Adulthood
Auteur: Castren, E., Elgersma, Y., Maffei, L., Hagerman, R.
Magazine: Journal of Neuroscience

Titel: GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility
Auteur: Judson, Matthew C., Wallace, Michael L., Sidorov, Michael S., Burette, Alain C., Gu, Bin, van Woerden, Geeske M., King, Ian F., Han, Ji Eun, Zylka, Mark J., Elgersma, Ype, Weinberg, Richard J., Philpot, Benjamin D.
Magazine: Neuron

Titel: Ca2+/Calmodulin-dependent Protein Kinase II  ( CaMKII) Controls the Activity of the Dopamine Transporter: IMPLICATIONS FOR ANGELMAN SYNDROME
Auteur: Steinkellner, T., Yang, J.-W., Montgomery, T. R., Chen, W.-Q., Winkler, M.-T., Sucic, S., Lubec, G., Freissmuth, M., Elgersma, Y., Sitte, H. H., Kudlacek, O.
Magazine: Journal of Biological Chemistry

Titel: Neurodevelopmental disease: A molecular tightrope

Titel: The Role of UBE2A and UBE3A in Motor- and Cognitive Function
Auteur: C.F. Bruinsma

Titel: Dissociation of locomotor and cerebellar deficits in Ube3a mice
Auteur: Y. Elgersma

Titel: A critical role for UBE3A in brain development
Auteur: Y. Elgersma

Titel: Structural and functional analysis of Ube3a/E6AP
Auteur: B. Distel

Titel: Model Systems to study UBE3A/E6AP function
Auteur: B. Distel

Titel: Understanding the molecular mechanisms underlying Angelman Syndrome
Auteur: Ype Elgersma

Titel: Understanding the molecular mechanisms underlying Angelman Syndrome
Auteur: Ype Elgersma

Titel: UBE3 gene reinstatement identifies distinct treatment windows in a mouse model for Angelman syndrome
Auteur: Ype Elgersma

Titel: Understanding the molecular mechanisms underlying Angelman Syndrome
Auteur: Ype Elgersma